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xyy syndrome famous people

Boys with XYY syndrome also known as 47,XYY might be taller than other boys. [3] [9] Usually, symptoms are subtle and subjects do not realize they are affected. My parents wanted me very badly and did in vitro fertilization to have me. Symptoms in a baby who has XYY syndrome can include: Symptoms in a young child or teenager with XYY syndrome can include: In adults, infertility is a possible symptom of XYY syndrome. Even the much less common 48,XXYY[29] had been discovered in 1960, a year before 47,XYY. That is, men with XYY syndrome are not more or less likely than other men to have children with XYY syndrome. There are usually few symptoms. [6][13] In Edinburgh, 54% of 47,XYY boys (7 of 13) identified in a newborn screening program received remedial reading teaching compared to 18% (4 of 22) in an above-average-IQ control group of 46,XY boys matched by their father's social class. https://www.youtube.com/watch?v=ISsdSvJhniQ, Activist Janet Mock Flips the Script on Reporter: Asks Her to Prove Her Womanhood (https://www.youtube.com/watch?v=ISsdSvJhniQ), https://www.youtube.com/watch?v=ULofBtBAJn4, Live a Day in the Life of King Tut | National Geographic (https://www.youtube.com/watch?v=ULofBtBAJn4), https://www.youtube.com/watch?v=U_4_ZQMSZuw, Jamie Lee Curtis Opens Up on Her Drug Addiction and Recovery (https://www.youtube.com/watch?v=U_4_ZQMSZuw), https://www.youtube.com/watch?v=G1wsCworwWk, Tom Cruise Forces James Corden to Skydive (https://www.youtube.com/watch?v=G1wsCworwWk), https://www.youtube.com/watch?v=XeQYdyDsioY, Caster Semenya breaks her silence (https://www.youtube.com/watch?v=XeQYdyDsioY), https://www.youtube.com/watch?v=1v6gPQLxYpU, Caroline Cossey Let Me Live by Queen (https://www.youtube.com/watch?v=1v6gPQLxYpU), https://www.youtube.com/watch?v=aJFYLmqcVsU, The True Story behind The Danish Girl Gerda & Lili (https://www.youtube.com/watch?v=aJFYLmqcVsU), https://www.youtube.com/watch?v=hvE9fbDig, George Washington First U.S. President | Mini Bio | BIO (https://www.youtube.com/watch?v=hvE9fbDig), Top 10 Most Handsome Bachelors In The World, Top 10 Most Famous Lawyers in American History. National Organization of Rare Disorders (NORD): 47, XYY syndrome. Answer (1 of 9): Klinefelter's Syndrome is a genetic model assuming itself as XXY syndrome. The American Schonfeld was the first to advance the theory that Niccolo Paganini was affected by the Marfan syndrome. If it is diagnosed early, patient can receive the necessary help for them. His legacy will live until we are all alive.if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-netboard-1','ezslot_18',178,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-netboard-1-0'); He is the first who can never b forgotten because of his significant and awe-inspiring contribution to the United States of America. Umbrella organizations provide a range of services for patients, families, and disease-specific organizations. A study shows that 43% of boys, 39 out of 90, show symptoms of unintentional tremors and motor tics due to XYY syndrome. People normally have 46 chromosomes in each cell. [1] There are usually few symptoms. Research also helps doctors better understand how well a treatment works and can lead to new treatment discoveries. 47, XYY syndrome - About the Disease - Genetic and Rare Diseases Information Center National Center for Advancing Translational Sciences Browse by Disease About GARD Contact Us We recently launched the new GARD website and are still developing specific pages. At the same time he made public reports from Vanderbilt University showing no abnormal makeup of Speck's chromosomesGetty displayed a letter of Sept. 26, 1966, relating that photographic evidence of 18 cells from Speck's blood showed no chromosome abnormality. SyndromesPedia Medical Syndromes Information Portal. 12. [1], The condition is generally not inherited but rather occurs as a result of a random event during sperm development. XYY syndrome is a genetic condition that. XYY syndrome is a genetic condition found in males only. [55], In June 1970, The XYY Man was publishedthe first of seven Kenneth Royce spy novels whose fictional tall, intelligent, nonviolent XYY hero was a reformed expert cat burglar recruited by British intelligence for dangerous assignmentsand later adapted into a thirteen-episode British summer television series broadcast in 1976 and 1977. She worked as a model in South Africa and Paris. [6][11] The incidence of 47,XYY is not known to be affected by the parents' ages.[6][11]. If one of these atypical sperm cells contributes to the genetic makeup of a child, the child will have an extra Y-chromosome in each of the body's cells. [52][53], In December 1969, Lore Zech at the Karolinska Institute in Stockholm first reported intense fluorescence of the A T-rich distal half of the long arm of the Y chromosome in the nuclei of metaphase cells treated with quinacrine mustard. [47][48] Concurrently, through 1974, psychologist John Money at Johns Hopkins Hospital experimented on thirteen XYY boys and men (ages 15 to 37) in an unsuccessful attempt to treat their history of behavior problems by chemical castration using high-dose Depo-Proverawith side-effects of weight gain (avg. The other cell had 45, regarded by the Vanderbilt investigators as having no significance. Introduction. Many rare diseases have limited information. People with this condition are able to live completely normal lives. For the color model, see, The first XYY review article, by W. Michael Court Brown, a physician and world authority on radiation biology and cytogenetics, was published in December 1968, the month he died at age 50. The female karyotype is XX, but male- XY. It did what? Psychiatric evaluation, as well as langue assessment and reading assessment should be done if the patient presents with cognitive development delay [2,3]. In the last decades, many . The following treatment options may help address some of the most common effects of XYY syndrome. Not all affected patients have extra Y chromosome in all of their cells. Arthrogryposis is a congenital condition present at birth characterized by a stiffening of the joints. If your child has this syndrome, talk with their teacher, principal, and special education coordinators. [1] He was also selected in 1997 by Vanity Fair as one of the best character actors in the United States. [51], In August 1976, Science published a retrospective cohort study by Educational Testing Service psychologist Herman Witkin and colleagues that screened the tallest 16% of men (over 184cm (6'0") in height) born in Copenhagen from 1944 to 1947 for XXY and XYY karyotypes, and found an increased rate of minor criminal convictions for property crimes among sixteen XXY and twelve XYY men may be related to the lower intelligence of those with criminal convictions, but found no evidence that XXY or XYY men were inclined to be aggressive or violent. What to Expect. [37] After learning that convicted mass murderer Richard Speck had been karyotyped, Telfer not only incorrectly assumed the acne-scarred Speck was XYY, but reached the false conclusion that Speck was the archetypical XYY maleor "supermale" as Telfer referred to XYY males outside of peer-reviewed scientific journals. She was renowned when she attempted to compete in the 1976 womens single competition but was initially excluded due to the current rule that allowed only two X chromosomes for female contestants, which became a barrier for her successful career.if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-box-4','ezslot_23',177,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-box-4-0');if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-box-4','ezslot_24',177,'0','1'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-box-4-0_1');.box-4-multi-177{border:none!important;display:block!important;float:none!important;line-height:0;margin-bottom:7px!important;margin-left:auto!important;margin-right:auto!important;margin-top:7px!important;max-width:100%!important;min-height:250px;padding:0;text-align:center!important}. Talking about her history of having Klinefelter syndrome, she was born and raised a male; she wrote an autobiography. [21] These men could be diagnosed with infertility as a result of oligospermia or sperm chromosomal abnormalities. George Washington, the once President of the United States was rumored to have been affected by klinefelter's syndrome. It is rare that these men have sons. And this also became evidence of him having this syndrome. It is caused by the presence of an extra Y chromosome. Finally, in 2005 she immigrated to Thailand, and since then, she lives in Bangkok with her family. Rare disease umbrella organizations focus on improving the lives of all those impacted by rare diseases through education and advocacy efforts. XYY Syndrome. if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-leader-2','ezslot_11',179,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-leader-2-0'); Klinefelter syndrome has always been there, and because of this, many people have been void and deprived of opportunities that could have boosted their careers. Males typically have one X chromosome and one Y chromosome (XY). 26lbs.) In males, this typically includes one X chromosome and one Y chromosome (XY). This error is called nondisjunction. Other symptoms can include problems with spoken language and processing spoken words, coordination problems, weaker muscles, hand tremors, and behavioral problems. XYY syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Current clinical studies can be found by using ClincalTrials.gov. Why do men commit crimes of violence? Other symptoms can include problems with spoken language and processing spoken words, coordination problems, weaker muscles, hand tremors, and behavioral difficulties. It may even help improve diagnosis and treatment of more common diseases. He is an American basketball player who played two years of college basketball for Baylor University. XYY syndrome can be detected by using diagnostic tests during pregnancy. She said that doctors told her parents that her genitals were incorrect or something wrong or unusual. People with Klinefelter syndrome are ordinary like us, and they deserve to live normally as we do. aggressive/antisocial/criminal behavior (1-2%) normal sexual characteristics/function. Austin is undergoing a long procedure to battle the effects of Marfan syndrome. The earliest known case of XYY Syndrome was in the 1960's was Avery Sandburg In 1974, a psychologist named John Money experimented with 13 XYY boys by giving them a high dosage of Depo-Provera, resulting in weight gain and suicide Posted by Unknown at 7:12 PM Email ThisBlogThis!Share to TwitterShare to FacebookShare to Pinterest 2 comments: Summary XYY syndrome is a rare chromosomal disorder that affects males. When the chromosome constitution 47, XYY was discovered in 1961, individuals with this chromosome pattern were called XYY males. People who have the XYY syndrome can be have a greater motivation towards killing and be more sadistic (Vronsky 247). Create unique images that will blow your mind with our AI tool. Troye suffers from a mild form of Marfan syndrome. Top 10 Richest & Successful Guitarists in The Top 10 Richest Jamaicans Net Worth Famous Billionaires. [2] The condition occurs in about 1 in 1,000 male births. Researchers such as molecular geneticists are challenging notions that XYY syndrome has a correlation to criminal, anti-social and/or abnormal behavior. 5'11", range: 5'7" to 6'2"), had a 47,XYY karyotype, and mischaracterized them as aggressive and violent criminals. For some diseases, symptoms may begin in a single age range or several age ranges. The rest are diagnosed after any of a variety of symptoms, including fertility problems (5%)[24] have been seen. He was born on September 27, 1987, in Ohio, and is best known as the former lead vocalist of the bands Attack Attack! and Of Mice & Men.. Cell division with nondisjuction happens spontaneously and it is not inherited. Educational therapy: Some people with XYY syndrome have learning disabilities. [5] In Edinburgh, Scotland, eight 47,XYY boys born 19671972 and identified in a newborn screening programme had an average height of 188.1cm (6'2") at age 18their fathers' average height was 174.1cm (5'8.mw-parser-output .frac{white-space:nowrap}.mw-parser-output .frac .num,.mw-parser-output .frac .den{font-size:80%;line-height:0;vertical-align:super}.mw-parser-output .frac .den{vertical-align:sub}.mw-parser-output .sr-only{border:0;clip:rect(0,0,0,0);height:1px;margin:-1px;overflow:hidden;padding:0;position:absolute;width:1px}12"), their mothers' average height was 162.8cm (5'4"). The signs and symptoms of KSin young boys and teenagers may include: Note since KS can be hard to notice, many parents dont know their child has the syndrome until he shows delays in puberty. However, she said she was willing to become a girl, although she had been diagnosed with Klinefelter syndrome. Cell division process, during which sperm cells with extra Y chromosome occur We discuss the vaccines to get during pregnancy and the ones to, Retinol products are not recommended during pregnancy. In males, this typically includes one X chromosome and one Y chromosome (XY). In September 1931, however, Lili Elbe died in one of the operations to transplant her uterus; she had stopped drawing and had no children of her own. [10] Most 47,XYY males have normal sexual development and have normal fertility. [70] For the eleven of fourteen boys with siblings, in nine instances their siblings were stronger academically, but in one case the subject was performing equal to, and in another case superior to, his siblings. It was rumored that Michael Phelps, however, he tested negative for it. As I already discussed that this syndrome gives a lot of changes to a persons body. Before climax, people with a penis can release a fluid known as pre-cum or pre-ejaculation. [9], Prenatal testosterone levels are normal in 47,XYY males. The exact diagnosis can be made by detecting an extra Y chromosome in chromosomal analysis and by evaluating the patient. XYY mosaicism occurs as a random event during early stages of embryonic development. Dr. Pergament said he and Dr. Sato, a research fellow, had absolutely no connection with the Speck case and never examined Speck. Peter earned a place in cinematic history for his role as Chewbacca in the Star Wars franchise. In some patient there is also delay in motor function development. [33], In May 1969, at the annual meeting of the American Psychiatric Association, Telfer and her Elwyn Institute colleagues reported that case studies of the institutionalized XYY and XXY males they had found convinced them that XYY males had been falsely stigmatized and that their behavior may not be significantly different from chromosomally normal 46,XY males. Reference: Data from the Newborn Screening Codingand Terminology Guide is available here. About 1 in 1,000 boys have it. You can learn more about how we ensure our content is accurate and current by reading our. Physical exam. Caster Semenya OIB is a middle-distance runner from South Africa and a gold medalist.if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-netboard-2','ezslot_21',124,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-netboard-2-0'); At the 2009 World Championships with a timescale of 1,55.45, at the 2016 Summer Olympics, she has won gold in the 800m womens race and 1:55.16 at the 2017 World Championships. . ON THE BASIS OF EXISTING EVIDENCE, THE FREQUENCY OF 47,XYY MALES AT BIRTH APPEARS TO BE ABOUT 1.5 PER 1,000. "Xyy" redirects here. Humans have 46 chromosomes- 22 pairs of somatic chromosomes and 1 pair of sex chromosomes. [54] In April 1970, Peter Pearson and Martin Bobrow at the MRC Population Genetics Unit in Oxford and Canino Vosa at the University of Oxford reported fluorescent "male" sex chromatin bodies in the nuclei of interphase cells in buccal smears treated with quinacrine dihydrochloride, which could be used to screen for Y chromosome aneuploidies like 47,XYY. However, the archaeologist in Egypt found his tomb in 1922, and it was astonishing. The syndrome can affect different stages of language, physical, and social development. during the 1960s and 1970s, studies of persons with ks and 47,xyy identified an increased frequency in hospitals for mentally handicapped, 11 and men with 47,xyy seemed to be over-represented in prisons. 47, XYY syndrome is caused by having an extra copy of the Y chromosome in every cell of the body. The violent crimes in the XYY men were 8.4%, while only 1.8% in XY males. XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome. I started getting speech help when I was 1 year old. He died of lung cancer at age 57 in Italy. Previous 1 answer Next Im 99% sure that Brendon Urie has jacobsen, but i dont know Posted Oct 25, 2018 by Caitlan 100 Celebrities with Jacobsen Syndrome Your answer In the latter case, a male may have some cells that are not affected. [51] After April 1975, screening of newborns was discontinuedchanges to informed consent procedures and pressure from additional advocacy groups, including the Children's Defense Fund, having led to the discontinuation of the last active U.S. newborn screening programs for sex chromosome abnormalities in Boston and Denver. Find people with XYY Syndrome through the map. It can affect physical and mental development. National Center for Advancing Translational Sciences, 47,XYY syndrome; Disomy Y; Double Y; Double Y syndrome; Jacobs syndrome; XYY Karyotype; XYY syndrome; Y disomy; YY syndrome. It can be difficult to diagnose since many sufferers have only a few typical symptoms and no specific biochemical or histologic changes. There are usually no symptoms suggesting this syndrome at birth. Before undergoing her first surgery, her physicians had been told with firmness and determination thatLili Elbehad more female than male hormones and likely had what is now known asKlinefeltersyndrome. [59] The false stereotype of XYY boys and men as violent criminals has also been used as a plot device in the horror films Il gatto a nove code in February 1971 (dubbed into English as The Cat o' Nine Tails in May 1971) and Alien 3 in May 1992. Some 47,XYY patients have been found to have genitourinary malformations. Like Down syndrome and other autosomal problems, sex chromosome gross abnormalities can be diagnosed before birth by amniocentesis and chorionic villi sampling. Persons with this condition also have normal sexual development and they are able to father children. It did not deter people from making these speculations even though he was married to 3 children, and the explanation is attached to it. This condition was initially discovered in the 1960s. [50] The Boston study, led by Harvard Medical School child psychiatrist Stanley Walzer at Children's Hospital, was unique among the seven newborn screening studies in that it only screened newborn boys (non-private-ward newborn boys at the Boston Hospital for Women) and was funded in part by grants from the NIMH Center for Studies of Crime and Delinquency. Boys with XYY syndrome also known as 47,XYY might be taller than other boys. XYY syndrome is a rare chromosomal health condition, which is a type of genetic disorder. People who have KS have an increased risk for autoimmune disorders, like rheumatoid arthritis, lupus, and Sjogrens syndrome. Healthline Media does not provide medical advice, diagnosis, or treatment. Her looks might still keep up, and many people think so. Of these, approximately 30% are diagnosed prenatally. People with this condition are able to live completely normal lives. In 2009, he won the Silver XYY SYNDROME STORIES. [46] In December 1969, with a grant from the NIMH Center for Studies of Crime and Delinquency, cytogeneticist Digamber Borgaonkar at Johns Hopkins Hospital began a chromosome survey of (predominantly African-American) boys ages 8 to 18 in all Maryland institutions for delinquent, neglected, or mentally ill juveniles, which was suspended from FebruaryMay 1970 due to an American Civil Liberties Union (ACLU) lawsuit about the lack of informed consent. An incident in chromosome separation during anaphase II (of meiosis II) called nondisjunction can result in sperm cells with an extra copy of the Y-chromosome. The 47,XYY syndrome is an aneuploidy of sex chromosomes in which a human male receives an extra Y-chromosome of paternal origin, giving a total of 47 chromosomes instead of the much more common 46. . His symptoms, as we and other laboratories tend to think of them, are: extremely tall stature, long limbs and strikingly long arm span, facial acne, mild mental retardation, severe mental illness (including psychosis) and aggressive, antisocial behavior with a long history of arrests, frequently beginning at an early age.On reading newspaper accounts of Richard Speck, who murdered eight Chicago student nurses in 1966, we noted all these traits and therefore concluded that Speck was a likely candidate for the XYY disorder. TroyeSivan started off as a singer in 2006 and in 2008 he released his first original music album. Eventually, Moore was diagnosed with Klinefelter syndrome. There are a number of other syndromes that can cause motor and cognitive development delays. [17], Approximately half of 47,XYY boys identified by newborn screening programs had learning difficultiesa higher proportion than found among siblings and above-average-IQ control groups. Presentation. Learn more about Fabry disease, including its symptoms, what causes it, and how it's treated. (adsbygoogle=window.adsbygoogle||[]).push({}); Klinefelter syndrome is also a kind of hardship that halts the happiness and success of many people.var cid='6538307557';var pid='ca-pub-5656155109851412';var slotId='div-gpt-ad-worldstopinsider_com-medrectangle-3-0';var ffid=2;var alS=2021%1000;var container=document.getElementById(slotId);container.style.width='100%';var ins=document.createElement('ins');ins.id=slotId+'-asloaded';ins.className='adsbygoogle ezasloaded';ins.dataset.adClient=pid;ins.dataset.adChannel=cid;if(ffid==2){ins.dataset.fullWidthResponsive='true';} XYY syndrome males inherit an extra Y chromosome . XXYY Syndrome is the name attached to the cluster of symptoms that arise as a result of the 48,XXYY chromosome pattern. She was later determined to identify herself as a lesbian. In 2005, Austin formed Call It Even with his high school friends. Besides that, Tom cruise has a circle form and primarily gives feminine looks when we critically analyze his features. Your email address will not be published. Healthcare professionals can help treat these issues. 47,XYY syndrome is characterized by an extra copy of the Y chromosome in each of an individual's cells. These data included a total of 10,086 karyotype data of the . [33][34][35][36] Over the next decade, almost all published XYY studies were on height-selected, institutionalized XYY males. Downs SM, van Dyck PC, Rinaldo P, et al. A genetic condition when a male is born The condition is generally not inherited but rather occurs as . XYY syndrome cant be cured. Klinefelter syndrome ( KS ), also known as 47,XXY, is an aneuploid genetic condition where a male has an additional copy of the X chromosome. [50][65] These seven studiesthe only unbiased studies of unselected individuals with sex chromosome abnormalitieshave replaced the older, biased studies of institutionalized individuals in understanding the development of individuals with sex chromosome abnormalities. Learn about its symptoms, causes, and. But what astonishing and bewildering is that Tom Cruise is another prominent person who has been rumored to have Klinefelter syndrome. "It was agreed," he said, "that the results would not be disclosed unless I wished them disclosed. Current clinical studies can be found by using ClinicalTrials.gov(see below). This means that instead of one X chromosome and Y chromosome, there are two Y chromosomes and one X chromosome. Are you shocked like me, yeah? Five to 10 boys with XYY syndrome are born in the United States each day. But treatments can help reduce its symptoms and effects, especially if its diagnosed early. [36] In November 1974, Science for the People went public with their objections to the Boston XYY study in a press conference and a New Scientist article alleging inadequate informed consent, a lack of benefit (since no specific treatment was available) but substantial risk (by stigmatization with a false stereotype) to the subjects, and that the unblinded experimental design could not produce meaningful results regarding the subjects' behavior. Unintended body movements such as shaking hands and muscle spasms are common symptoms of XYY syndrome. The extra Y chromosome is usually eliminated during the process of spermatogenesis [1]. This can produce 46,XY/47,XYY mosaics.[22]. This condition in most cases in not inherited. Dr. Catherine Ward Melver Dr. Catherine Ward Melver is a medical genetics doctor and one of many celebrities with Turner syndrome. [15][17][18][19], In prospective studies of 47,XYY boys identified by newborn screening programs, the IQ scores of 47,XYY boys were usually slightly lower than those of their siblings. [6][11][12][13], In contrast to the other common sex chromosome aneuploidies47,XXX and 47,XXY (Klinefelter syndrome)the average IQ scores of 47,XYY boys identified by newborn screening programs were not reduced compared to the general population. Researchers dont believe that theres any genetic predisposition to it. XYY Syndrome. Some syndromes present with similar symptoms to XYY syndrome. View map. Most individuals with 47,XYY syndrome have normal production of the male sex hormone testosterone . [11][66], In May 1997, Nature Genetics published the discovery by Ercole Rao and colleagues of the X/Y chromosome pseudoautosomal region (PAR1) SHOX gene, haploinsufficiency of which leads to short stature in Turner syndrome (45,X). 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Is generally not inherited but rather occurs as ClinicalTrials.gov ( see below.! As I already discussed that this syndrome gives a lot of changes to a persons.... Few typical symptoms and effects, especially if its diagnosed early the results not! By Klinefelter & # x27 ; s syndrome crimes in the United States was rumored that Phelps. Of learning disabilities eliminated during the process of spermatogenesis [ 1 ] he was also selected in 1997 by Fair. Called XYY males at birth APPEARS to be about 1.5 PER 1,000 that Niccolo Paganini was affected the! Top 10 Richest & Successful Guitarists in the United States each day,,., or treatment, which is a rare chromosomal health condition, is. In some patient there is also delay in motor function development and Y chromosome ( XY ) of. There is also delay in motor function development aggressive/antisocial/criminal behavior ( 1-2 % ) normal characteristics/function. This chromosome pattern ] [ 9 ], Prenatal testosterone levels are normal in,! Can lead to new treatment discoveries Silver XYY syndrome parents that her genitals were incorrect or something or. Famous Billionaires with a xyy syndrome famous people can release a fluid known as Jacobs syndrome, she in! And Paris talk with their teacher, principal, and disease-specific organizations constitution 47, XYY patients extra.

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xyy syndrome famous people